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Structural basis of selectivity and neutralizing activity of a TGFα/epiregulin specific antibody
Recent studies have implicated a role of the epidermal growth factor receptor (EGFR) pathway in kidney disease. Skin toxicity associated with therapeutics which completely block the EGFR pathway precludes their use in chronic dosing. Therefore, we developed antibodies which specifically neutralize t...
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| Publicado no: | Protein Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5079263/ https://ncbi.nlm.nih.gov/pubmed/27543934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3023 |
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