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Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing

Antibody therapeutics are one of the most important classes of drugs. Antibody structures have become an integral part of predicting the behavior of potential therapeutics, either directly or as the basis of modeling. Structures of Fab:antigen complexes have even greater value. While the crystalliza...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Lieu, Ricky, Antonysamy, Stephen, Druzina, Zhanna, Ho, Carolyn, Kang, N. Rebecca, Pustilnik, Anna, Wang, Jing, Atwell, Shane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485759/
https://ncbi.nlm.nih.gov/pubmed/32915778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232311
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