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Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing

Antibody therapeutics are one of the most important classes of drugs. Antibody structures have become an integral part of predicting the behavior of potential therapeutics, either directly or as the basis of modeling. Structures of Fab:antigen complexes have even greater value. While the crystalliza...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lieu, Ricky, Antonysamy, Stephen, Druzina, Zhanna, Ho, Carolyn, Kang, N. Rebecca, Pustilnik, Anna, Wang, Jing, Atwell, Shane
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485759/
https://ncbi.nlm.nih.gov/pubmed/32915778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232311
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