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Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody

CXCR1 and CXCR2 signaling play a critical role in neutrophil migration, angiogenesis, and tumorigenesis and are therefore an attractive signaling axis to target in a variety of indications. In human, a total of seven chemokines signal through these receptors and comprise the ELR(+)CXC chemokine fami...

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Bibliografiska uppgifter
I publikationen:MAbs
Huvudupphovsmän: Boyles, Jeffrey S., Beidler, Catherine B., Strifler, Beth A., Girard, Daniel S., Druzina, Zhanna, Durbin, Jim D., Swearingen, Michelle L., Lee, Linda N., Kikly, Kristine, Chintharlapalli, Sudhakar, Witcher, Derrick R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671035/
https://ncbi.nlm.nih.gov/pubmed/33183151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2020.1831880
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