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ELR+ CXC chemokines and oncogenic Ras-mediated tumorigenesis

The small GTPase Ras is mutated to remain in the active oncogenic state in one-third of human cancers, thereby promoting tumorigenesis. It has recently come to light that one consequence of oncogenic Ras signaling is secretion of cytokines vascular endothelial growth factor (VEGF), interleukin 6 (IL...

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Autori principali: O'Hayer, Kevin M., Brady, Donita C., Counter, Christopher M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783001/
https://ncbi.nlm.nih.gov/pubmed/19805574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp198
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