Correlation between amount of virus with altered nucleotide sequence and the monkey test for acceptability of oral poliovirus vaccine.

Production of live attenuated oral poliomyelitis vaccine (OPV) requires rigorous neurovirulence safety testing of each vaccine lot, currently carried out in monkeys. It has been reported that a change from 472-U to 472-C in the type 3 OPV RNA is associated with an increased histologic lesion score p...

Celý popis

Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Chumakov, K M, Powers, L B, Noonan, K E, Roninson, I B, Levenbook, I S
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1991
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50777/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846038/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.1.199
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!