Transgenic mice carrying the human poliovirus receptor: new animal models for study of poliovirus neurovirulence.

Recombinant viruses between the virulent Mahoney and attenuated Sabin 1 strains of poliovirus type 1 were subjected to neurovirulence tests using a transgenic (Tg) mouse line, ICR-PVRTg1, that carried the human poliovirus receptor gene. The Tg mice were inoculated intracerebrally with these recombin...

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Bibliografske podrobnosti
Main Authors: Horie, H, Koike, S, Kurata, T, Sato-Yoshida, Y, Ise, I, Ota, Y, Abe, S, Hioki, K, Kato, H, Taya, C
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC236503/
https://ncbi.nlm.nih.gov/pubmed/8289371
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