Transgenic mice carrying the human poliovirus receptor: new animal models for study of poliovirus neurovirulence.
Recombinant viruses between the virulent Mahoney and attenuated Sabin 1 strains of poliovirus type 1 were subjected to neurovirulence tests using a transgenic (Tg) mouse line, ICR-PVRTg1, that carried the human poliovirus receptor gene. The Tg mice were inoculated intracerebrally with these recombin...
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| 出版年: | J Virol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1994
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236503/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289371/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.2.681-688.1994 |
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