Transgenic mice carrying the human poliovirus receptor: new animal models for study of poliovirus neurovirulence.

Recombinant viruses between the virulent Mahoney and attenuated Sabin 1 strains of poliovirus type 1 were subjected to neurovirulence tests using a transgenic (Tg) mouse line, ICR-PVRTg1, that carried the human poliovirus receptor gene. The Tg mice were inoculated intracerebrally with these recombin...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Horie, H, Koike, S, Kurata, T, Sato-Yoshida, Y, Ise, I, Ota, Y, Abe, S, Hioki, K, Kato, H, Taya, C
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236503/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289371/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.2.681-688.1994
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