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Identification of a consistent pattern of mutations in neurovirulent variants derived from the sabin vaccine strain of poliovirus type 2.

Complete nucleotide sequencing of the RNAs of two unrelated neurovirulent isolates of Sabin-related poliovirus type 2 revealed that two nucleotides and one amino acid (amino acid 143 in the major capsid protein VP1) consistently departed from the sequences of the nonneurovirulent poliovirus type 2 7...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Equestre, M, Genovese, D, Cavalieri, F, Fiore, L, Santoro, R, Perez Bercoff, R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240633/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1850043/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.5.2707-2710.1991
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