Determinants of attenuation and temperature sensitivity in the type 1 poliovirus Sabin vaccine.
To identify determinants of attenuation in the poliovirus type 1 Sabin vaccine strain, a series of recombinant viruses were constructed by using infectious cDNA clones of the virulent type 1 poliovirus P1/Mahoney and the attenuated type 1 vaccine strain P1/Sabin. Intracerebral inoculation of these v...
Guardado en:
| Publicado en: | J Virol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1995
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7609067/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.4972-4978.1995 |
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