Determinants of attenuation and temperature sensitivity in the type 1 poliovirus Sabin vaccine.

To identify determinants of attenuation in the poliovirus type 1 Sabin vaccine strain, a series of recombinant viruses were constructed by using infectious cDNA clones of the virulent type 1 poliovirus P1/Mahoney and the attenuated type 1 vaccine strain P1/Sabin. Intracerebral inoculation of these v...

Full description

Saved in:
Bibliographic Details
Main Authors: Bouchard, M J, Lam, D H, Racaniello, V R
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC189313/
https://ncbi.nlm.nih.gov/pubmed/7609067
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items