Determinants of attenuation and temperature sensitivity in the type 1 poliovirus Sabin vaccine.

To identify determinants of attenuation in the poliovirus type 1 Sabin vaccine strain, a series of recombinant viruses were constructed by using infectious cDNA clones of the virulent type 1 poliovirus P1/Mahoney and the attenuated type 1 vaccine strain P1/Sabin. Intracerebral inoculation of these v...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Bouchard, M J, Lam, D H, Racaniello, V R
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7609067/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.4972-4978.1995
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