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Auxotrophy-based High Throughput Screening assay for the identification of Bacillus subtilis stringent response inhibitors

The stringent response is a central adaptation mechanism that allows bacteria to adjust their growth and metabolism according to environmental conditions. The functionality of the stringent response is crucial for bacterial virulence, survival during host invasion as well as antibiotic resistance an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Andresen, Liis, Varik, Vallo, Tozawa, Yuzuru, Jimmy, Steffi, Lindberg, Stina, Tenson, Tanel, Hauryliuk, Vasili
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075769/
https://ncbi.nlm.nih.gov/pubmed/27775002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35824
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