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Auxotrophy-based High Throughput Screening assay for the identification of Bacillus subtilis stringent response inhibitors

The stringent response is a central adaptation mechanism that allows bacteria to adjust their growth and metabolism according to environmental conditions. The functionality of the stringent response is crucial for bacterial virulence, survival during host invasion as well as antibiotic resistance an...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Andresen, Liis, Varik, Vallo, Tozawa, Yuzuru, Jimmy, Steffi, Lindberg, Stina, Tenson, Tanel, Hauryliuk, Vasili
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075769/
https://ncbi.nlm.nih.gov/pubmed/27775002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35824
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