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Auxotrophy-based High Throughput Screening assay for the identification of Bacillus subtilis stringent response inhibitors

The stringent response is a central adaptation mechanism that allows bacteria to adjust their growth and metabolism according to environmental conditions. The functionality of the stringent response is crucial for bacterial virulence, survival during host invasion as well as antibiotic resistance an...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Andresen, Liis, Varik, Vallo, Tozawa, Yuzuru, Jimmy, Steffi, Lindberg, Stina, Tenson, Tanel, Hauryliuk, Vasili
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075769/
https://ncbi.nlm.nih.gov/pubmed/27775002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35824
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