The ribosomal A-site finger is crucial for binding and activation of the stringent factor RelA

During amino acid starvation the Escherichia coli stringent response factor RelA recognizes deacylated tRNA in the ribosomal A-site. This interaction activates RelA-mediated synthesis of alarmone nucleotides pppGpp and ppGpp, collectively referred to as (p)ppGpp. These two alarmones are synthesized...

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Publicat a:Nucleic Acids Res
Autors principals: Kudrin, Pavel, Dzhygyr, Ievgen, Ishiguro, Kensuke, Beljantseva, Jelena, Maksimova, Elena, Oliveira, Sofia Raquel Alves, Varik, Vallo, Payoe, Roshani, Konevega, Andrey L, Tenson, Tanel, Suzuki, Tsutomu, Hauryliuk, Vasili
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Nucleic Acid Enzymes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829649/
https://ncbi.nlm.nih.gov/pubmed/29390134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky023
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