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Composition of the outgrowth medium modulates wake-up kinetics and ampicillin sensitivity of stringent and relaxed Escherichia coli

The transition of Escherichia coli from the exponential into the stationary phase of growth induces the stringent response, which is mediated by the rapid accumulation of the alarmone nucleotide (p)ppGpp produced by the enzyme RelA. The significance of RelA’s functionality during the transition in t...

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Pubblicato in:Sci Rep
Autori principali: Varik, Vallo, Oliveira, Sofia Raquel Alves, Hauryliuk, Vasili, Tenson, Tanel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770409/
https://ncbi.nlm.nih.gov/pubmed/26923949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22308
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