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High expression of human beta S- and alpha-globins in transgenic mice: hemoglobin composition and hematological consequences.

A line of transgenic mice (alpha H beta S-11; where alpha H is human alpha-globin) was created in which the human beta S and human alpha 2 globin genes, each linked to the beta-globin locus control region, were cointegrated into the mouse genome. On a normal genetic background, the transgenic mice p...

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Detalles Bibliográficos
Main Authors: Fabry, M E, Nagel, R L, Pachnis, A, Suzuka, S M, Costantini, F
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC50716/
https://ncbi.nlm.nih.gov/pubmed/1465454
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