High expression of human beta S- and alpha-globins in transgenic mice: hemoglobin composition and hematological consequences.

A line of transgenic mice (alpha H beta S-11; where alpha H is human alpha-globin) was created in which the human beta S and human alpha 2 globin genes, each linked to the beta-globin locus control region, were cointegrated into the mouse genome. On a normal genetic background, the transgenic mice p...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Fabry, M E, Nagel, R L, Pachnis, A, Suzuka, S M, Costantini, F
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1992
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50716/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1465454/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.24.12150
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