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Expression of human alpha-globin and mouse/human hybrid beta-globin genes in murine hemopoietic stem cells transduced by recombinant retroviruses.

Murine cell lines releasing helper-free recombinant retroviruses containing human alpha-globin and mouse/human hybrid beta-globin genes were generated. The expression of the hybrid beta-globin gene but not the human alpha-globin gene was regulated appropriately in infected mouse erythroid leukemia (...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Li, C L, Dwarki, V J, Verma, I M
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1990
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54107/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2349242/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.11.4349
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