High expression of human beta S- and alpha-globins in transgenic mice: hemoglobin composition and hematological consequences.
A line of transgenic mice (alpha H beta S-11; where alpha H is human alpha-globin) was created in which the human beta S and human alpha 2 globin genes, each linked to the beta-globin locus control region, were cointegrated into the mouse genome. On a normal genetic background, the transgenic mice p...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50716/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1465454/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.24.12150 |
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