Beta-globin enhancers target expression of a heterologous gene to erythroid tissues of transgenic mice.
To examine the role of human beta-globin enhancers in tissue-specific and developmental regulation, a hybrid beta-globin-simian virus 40 gene was analyzed in transgenic mice. A beta-globin DNA fragment containing two previously defined enhancers stimulated transcription from the simian virus 40 prom...
Saved in:
| Published in: | Mol Cell Biol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
1989
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362549/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555696/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.10.4581-4584.1989 |
| Tags: |
No Tags, Be the first to tag this record!
|