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Beta-globin enhancers target expression of a heterologous gene to erythroid tissues of transgenic mice.

To examine the role of human beta-globin enhancers in tissue-specific and developmental regulation, a hybrid beta-globin-simian virus 40 gene was analyzed in transgenic mice. A beta-globin DNA fragment containing two previously defined enhancers stimulated transcription from the simian virus 40 prom...

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Detaylı Bibliyografya
Asıl Yazarlar: Magram, J, Niederreither, K, Costantini, F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1989
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC362549/
https://ncbi.nlm.nih.gov/pubmed/2555696
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