Beta-globin enhancers target expression of a heterologous gene to erythroid tissues of transgenic mice.
To examine the role of human beta-globin enhancers in tissue-specific and developmental regulation, a hybrid beta-globin-simian virus 40 gene was analyzed in transgenic mice. A beta-globin DNA fragment containing two previously defined enhancers stimulated transcription from the simian virus 40 prom...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1989
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362549/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555696/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.10.4581-4584.1989 |
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