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Regulated expression of the human beta globin gene in transgenic mice requires an upstream globin or nonglobin promoter.

Transgenic mice have been used extensively to study elements governing the erythroid-specific developmental switch from human fetal gamma to human adult beta globin. Previous work demonstrated that a small construct composed of hypersensitive site 2 (HS2) of the locus control region (LCR) linked to...

詳細記述

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書誌詳細
出版年:Mol Biol Cell
主要な著者: Anderson, K P, Lloyd, J A, Ponce, E, Crable, S C, Neumann, J C, Lingrel, J B
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Cell Biology 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275740/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8298193/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.10.1077
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