Regulated expression of the human beta globin gene in transgenic mice requires an upstream globin or nonglobin promoter.

Transgenic mice have been used extensively to study elements governing the erythroid-specific developmental switch from human fetal gamma to human adult beta globin. Previous work demonstrated that a small construct composed of hypersensitive site 2 (HS2) of the locus control region (LCR) linked to...

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Main Authors: Anderson, K P, Lloyd, J A, Ponce, E, Crable, S C, Neumann, J C, Lingrel, J B
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC275740/
https://ncbi.nlm.nih.gov/pubmed/8298193
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