Regulated expression of the human beta globin gene in transgenic mice requires an upstream globin or nonglobin promoter.

Transgenic mice have been used extensively to study elements governing the erythroid-specific developmental switch from human fetal gamma to human adult beta globin. Previous work demonstrated that a small construct composed of hypersensitive site 2 (HS2) of the locus control region (LCR) linked to...

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Publicado en:	Mol Biol Cell
Autores principales:	Anderson, K P, Lloyd, J A, Ponce, E, Crable, S C, Neumann, J C, Lingrel, J B
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Cell Biology 1993
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8298193/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.10.1077
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