Regulated expression of the human beta globin gene in transgenic mice requires an upstream globin or nonglobin promoter.
Transgenic mice have been used extensively to study elements governing the erythroid-specific developmental switch from human fetal gamma to human adult beta globin. Previous work demonstrated that a small construct composed of hypersensitive site 2 (HS2) of the locus control region (LCR) linked to...
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| Vydáno v: | Mol Biol Cell |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Cell Biology
1993
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8298193/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.10.1077 |
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