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Extending CRISPR-Cas9 Technology from Genome Editing to Transcriptional Engineering in the Genus Clostridium

The discovery and exploitation of the prokaryotic adaptive immunity system based on clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins have revolutionized genetic engineering. CRISPR-Cas tools have enabled extensive genome editing as well as effi...

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Библиографические подробности
Опубликовано в: :Appl Environ Microbiol
Главные авторы: Bruder, Mark R., Pyne, Michael E., Moo-Young, Murray, Chung, Duane A., Chou, C. Perry
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068152/
https://ncbi.nlm.nih.gov/pubmed/27496775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02128-16
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