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Extending CRISPR-Cas9 Technology from Genome Editing to Transcriptional Engineering in the Genus Clostridium
The discovery and exploitation of the prokaryotic adaptive immunity system based on clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins have revolutionized genetic engineering. CRISPR-Cas tools have enabled extensive genome editing as well as effi...
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Опубликовано в: : | Appl Environ Microbiol |
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Главные авторы: | , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
American Society for Microbiology
2016
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068152/ https://ncbi.nlm.nih.gov/pubmed/27496775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02128-16 |
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