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Extending CRISPR-Cas9 Technology from Genome Editing to Transcriptional Engineering in the Genus Clostridium

The discovery and exploitation of the prokaryotic adaptive immunity system based on clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins have revolutionized genetic engineering. CRISPR-Cas tools have enabled extensive genome editing as well as effi...

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Bibliografski detalji
Izdano u:Appl Environ Microbiol
Glavni autori: Bruder, Mark R., Pyne, Michael E., Moo-Young, Murray, Chung, Duane A., Chou, C. Perry
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068152/
https://ncbi.nlm.nih.gov/pubmed/27496775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02128-16
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