Extending CRISPR-Cas9 Technology from Genome Editing to Transcriptional Engineering in the Genus Clostridium

The discovery and exploitation of the prokaryotic adaptive immunity system based on clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins have revolutionized genetic engineering. CRISPR-Cas tools have enabled extensive genome editing as well as effi...

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Bibliographic Details
Published in:Appl Environ Microbiol
Main Authors: Bruder, Mark R., Pyne, Michael E., Moo-Young, Murray, Chung, Duane A., Chou, C. Perry
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068152/
https://ncbi.nlm.nih.gov/pubmed/27496775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02128-16
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