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Extending CRISPR-Cas9 Technology from Genome Editing to Transcriptional Engineering in the Genus Clostridium

The discovery and exploitation of the prokaryotic adaptive immunity system based on clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins have revolutionized genetic engineering. CRISPR-Cas tools have enabled extensive genome editing as well as effi...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Bruder, Mark R., Pyne, Michael E., Moo-Young, Murray, Chung, Duane A., Chou, C. Perry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068152/
https://ncbi.nlm.nih.gov/pubmed/27496775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02128-16
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