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Extending CRISPR-Cas9 Technology from Genome Editing to Transcriptional Engineering in the Genus Clostridium
The discovery and exploitation of the prokaryotic adaptive immunity system based on clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins have revolutionized genetic engineering. CRISPR-Cas tools have enabled extensive genome editing as well as effi...
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Veröffentlicht in: | Appl Environ Microbiol |
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Hauptverfasser: | , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
American Society for Microbiology
2016
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068152/ https://ncbi.nlm.nih.gov/pubmed/27496775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02128-16 |
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