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Profibrotic up-regulation of glucose transporter 1 by TGF-β involves activation of MEK and mammalian target of rapamycin complex 2 pathways
TGF-β plays a central role in the pathogenesis of fibroproliferative disorders. Defining the exact underlying molecular basis is therefore critical for the development of viable therapeutic strategies. Here, we show that expression of the facilitative glucose transporter 1 (GLUT1) is induced by TGF-...
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發表在: | FASEB J |
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Main Authors: | , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Federation of American Societies for Experimental Biology
2016
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5067255/ https://ncbi.nlm.nih.gov/pubmed/27480571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600428R |
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