Profibrotic TGFβ responses require the cooperative action of PDGF and ErbB receptor tyrosine kinases

Transforming growth factor β (TGFβ) has significant profibrotic activity both in vitro and in vivo. This reflects its capacity to stimulate fibrogenic mediators and induce the expression of other profibrotic cytokines such as platelet-derived growth factor (PDGF) and epidermal growth factor (EGF/Erb...

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Detalhes bibliográficos
Main Authors: Andrianifahanana, Mahefatiana, Wilkes, Mark C., Gupta, Shiv K., Rahimi, Rod A., Repellin, Claire E., Edens, Maryanne, Wittenberger, Joshua, Yin, Xueqian, Maidl, Elizabeth, Becker, Jackson, Leof, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804746/
https://ncbi.nlm.nih.gov/pubmed/23913859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-224907
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