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Sorting nexin 9 differentiates ligand-activated Smad3 from Smad2 for nuclear import and transforming growth factor β signaling

Transforming growth factor β (TGFβ) is a pleiotropic protein secreted from essentially all cell types and primary tissues. While TGFβ’s actions reflect the activity of a number of signaling networks, the primary mediator of TGFβ responses are the Smad proteins. Following receptor activation, these c...

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Bibliografiska uppgifter
I publikationen:Mol Biol Cell
Huvudupphovsmän: Wilkes, Mark C., Repellin, Claire E., Kang, Jeong-Han, Andrianifahanana, Mahefatiana, Yin, Xueqian, Leof, Edward B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626071/
https://ncbi.nlm.nih.gov/pubmed/26337383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-07-0545
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