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Data on the purification and crystallization of the loss-of-function von Willebrand disease variant (p.Gly1324Ser) of the von Willebrand factor A1 domain

von Willebrand factor׳s (VWF) primary hemostatic responsibility is to deposit platelets at sites of vascular injury to prevent bleeding. This function is mediated by the interaction between the VWF A1 domain and the constitutively active platelet receptor, GPIbα. The crystal structure of the A1 doma...

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Dettagli Bibliografici
Pubblicato in:Data Brief
Autori principali: Campbell, James C., Tischer, Alexander, Machha, Venkata, Moon-Tasson, Laurie, Sankaran, Banumathi, Kim, Choel, Auton, Matthew
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063811/
https://ncbi.nlm.nih.gov/pubmed/27761512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dib.2016.05.004
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