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The von Willebrand Factor A1-Collagen III Interaction is Independent of Conformation and Type 2 von Willebrand Disease Phenotype

The blood von Willebrand factor (VWF) mediates platelet adhesion to injured vessels by sequestering platelets from blood flow and depositing them to collagen and other exposed subendothelial matrix proteins. This process of capturing platelets to facilitate formation of platelet plugs occurs through...

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Pubblicato in:J Mol Biol
Autori principali: Machha, Venkata R., Tischer, Alexander, Moon-Tasson, Laurie, Auton, Matthew
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5186406/
https://ncbi.nlm.nih.gov/pubmed/27889474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.11.014
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