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Data on the purification and crystallization of the loss-of-function von Willebrand disease variant (p.Gly1324Ser) of the von Willebrand factor A1 domain

von Willebrand factor׳s (VWF) primary hemostatic responsibility is to deposit platelets at sites of vascular injury to prevent bleeding. This function is mediated by the interaction between the VWF A1 domain and the constitutively active platelet receptor, GPIbα. The crystal structure of the A1 doma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Data Brief
Hauptverfasser: Campbell, James C., Tischer, Alexander, Machha, Venkata, Moon-Tasson, Laurie, Sankaran, Banumathi, Kim, Choel, Auton, Matthew
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063811/
https://ncbi.nlm.nih.gov/pubmed/27761512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dib.2016.05.004
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