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SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage
SOX9 encodes a transcription factor that governs cell fate specification throughout development and tissue homeostasis. Elevated SOX9 is implicated in the genesis and progression of human tumors by increasing cell proliferation and epithelial-mesenchymal transition. We found that in response to UV i...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5062998/ https://ncbi.nlm.nih.gov/pubmed/27566146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw748 |
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