Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma

Sox9 has gained increasing importance both functionally and as a prognostic factor in cancer. We demonstrate a functional role for Sox9 in inducing a mesenchymal phenotype in lung ADC. We show that Sox9 mRNA and protein are overexpressed in lung ADC, particularly those with KRAS mutations. Sox9 expr...

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Detalhes bibliográficos
Main Authors: Capaccione, Kathleen M., Hong, Xuehui, Morgan, Katherine M., Liu, Wenyu, Bishop, Michael J., Liu, LianXin, Markert, Elke, Deen, Malik, Minerowicz, Christine, Bertino, Joseph R., Allen, Thaddeus, Pine, Sharon R.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116509/
https://ncbi.nlm.nih.gov/pubmed/25004243
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