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Extensively Parameterized Mutation–Selection Models Reliably Capture Site-Specific Selective Constraint
The mutation–selection model of coding sequence evolution has received renewed attention for its use in estimating site-specific amino acid propensities and selection coefficient distributions. Two computationally tractable mutation–selection inference frameworks have been introduced: One framework...
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| Publicado no: | Mol Biol Evol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5062325/ https://ncbi.nlm.nih.gov/pubmed/27512115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw171 |
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