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A Comparison of One-Rate and Two-Rate Inference Frameworks for Site-Specific dN/dS Estimation

Two broad paradigms exist for inferring [Formula: see text] the ratio of nonsynonymous to synonymous substitution rates, from coding sequences: (i) a one-rate approach, where [Formula: see text] is represented with a single parameter, or (ii) a two-rate approach, where [Formula: see text] and [Formu...

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Bibliografiska uppgifter
I publikationen:Genetics
Huvudupphovsmän: Spielman, Stephanie J., Wan, Suyang, Wilke, Claus O.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Genetics Society of America 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068842/
https://ncbi.nlm.nih.gov/pubmed/27535929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.185264
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