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Causes of evolutionary rate variation among protein sites

It has long been recognized that certain sites within a protein, such as sites in the protein core or catalytic residues in enzymes, are more conserved than are other sites. However, our understanding of rate variation among sites remains surprisingly limited. Recent progress to address this include...

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Detalhes bibliográficos
Publicado no:Nat Rev Genet
Main Authors: Echave, Julian, Spielman, Stephanie J., Wilke, Claus O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724262/
https://ncbi.nlm.nih.gov/pubmed/26781812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg.2015.18
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