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Causes of evolutionary rate variation among protein sites

It has long been recognized that certain sites within a protein, such as sites in the protein core or catalytic residues in enzymes, are more conserved than are other sites. However, our understanding of rate variation among sites remains surprisingly limited. Recent progress to address this include...

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Bibliografische gegevens
Gepubliceerd in:Nat Rev Genet
Hoofdauteurs: Echave, Julian, Spielman, Stephanie J., Wilke, Claus O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724262/
https://ncbi.nlm.nih.gov/pubmed/26781812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg.2015.18
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