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The utility of protein structure as a predictor of site-wise dN/dS varies widely among HIV-1 proteins

Protein structure acts as a general constraint on the evolution of viral proteins. One widely recognized structural constraint explaining evolutionary variation among sites is the relative solvent accessibility (RSA) of residues in the folded protein. In influenza virus, the distance from functional...

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書目詳細資料
發表在:J R Soc Interface
Main Authors: Meyer, Austin G., Wilke, Claus O.
格式: Artigo
語言:Inglês
出版: The Royal Society 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614493/
https://ncbi.nlm.nih.gov/pubmed/26468068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2015.0579
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