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The utility of protein structure as a predictor of site-wise dN/dS varies widely among HIV-1 proteins

Protein structure acts as a general constraint on the evolution of viral proteins. One widely recognized structural constraint explaining evolutionary variation among sites is the relative solvent accessibility (RSA) of residues in the folded protein. In influenza virus, the distance from functional...

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Detalles Bibliográficos
Publicado en:J R Soc Interface
Main Authors: Meyer, Austin G., Wilke, Claus O.
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614493/
https://ncbi.nlm.nih.gov/pubmed/26468068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2015.0579
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