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Integrating Sequence Variation and Protein Structure to Identify Sites under Selection
We present a novel method to identify sites under selection in protein-coding genes. Our method combines the traditional Goldman–Yang model of coding-sequence evolution with the information obtained from the 3D structure of the evolving protein, specifically the relative solvent accessibility (RSA)...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525147/ https://ncbi.nlm.nih.gov/pubmed/22977116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mss217 |
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