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Extensively Parameterized Mutation–Selection Models Reliably Capture Site-Specific Selective Constraint

The mutation–selection model of coding sequence evolution has received renewed attention for its use in estimating site-specific amino acid propensities and selection coefficient distributions. Two computationally tractable mutation–selection inference frameworks have been introduced: One framework...

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Podrobná bibliografie
Vydáno v:Mol Biol Evol
Hlavní autoři: Spielman, Stephanie J., Wilke, Claus O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062325/
https://ncbi.nlm.nih.gov/pubmed/27512115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw171
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