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Limited Utility of Residue Masking for Positive-Selection Inference

Errors in multiple sequence alignments (MSAs) can reduce accuracy in positive-selection inference. Therefore, it has been suggested to filter MSAs before conducting further analyses. One widely used filter, Guidance, allows users to remove MSA positions aligned with low confidence. However, Guidance...

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Detalhes bibliográficos
Main Authors: Spielman, Stephanie J., Dawson, Eric T., Wilke, Claus O.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137709/
https://ncbi.nlm.nih.gov/pubmed/24899665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msu183
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