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Limited Utility of Residue Masking for Positive-Selection Inference

Errors in multiple sequence alignments (MSAs) can reduce accuracy in positive-selection inference. Therefore, it has been suggested to filter MSAs before conducting further analyses. One widely used filter, Guidance, allows users to remove MSA positions aligned with low confidence. However, Guidance...

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Détails bibliographiques
Auteurs principaux: Spielman, Stephanie J., Dawson, Eric T., Wilke, Claus O.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137709/
https://ncbi.nlm.nih.gov/pubmed/24899665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msu183
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