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Limited Utility of Residue Masking for Positive-Selection Inference

Errors in multiple sequence alignments (MSAs) can reduce accuracy in positive-selection inference. Therefore, it has been suggested to filter MSAs before conducting further analyses. One widely used filter, Guidance, allows users to remove MSA positions aligned with low confidence. However, Guidance...

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Bibliografiske detaljer
Main Authors: Spielman, Stephanie J., Dawson, Eric T., Wilke, Claus O.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137709/
https://ncbi.nlm.nih.gov/pubmed/24899665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msu183
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