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Cancer stem cell drugs target K-ras signaling in a stemness context
Cancer stem cells (CSCs) are considered to be responsible for treatment relapse and have therefore become a major target in cancer research. Salinomycin is the most established CSC inhibitor. However, its primary mechanistic target is still unclear, impeding the discovery of compounds with similar a...
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| Publicado no: | Oncogene |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5057041/ https://ncbi.nlm.nih.gov/pubmed/26973241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.59 |
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