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SPRED1 Interferes with K-ras but Not H-ras Membrane Anchorage and Signaling
The Ras/mitogen-activated protein kinase (MAPK) signaling pathway is tightly controlled by negative feedback regulators, such as the tumor suppressor SPRED1. The SPRED1 gene also carries loss-of-function mutations in the RASopathy Legius syndrome. Growth factor stimulation translocates SPRED1 to the...
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| 出版年: | Mol Cell Biol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5038144/ https://ncbi.nlm.nih.gov/pubmed/27503857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00191-16 |
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